Inc. revealed today that Lightbeam Health Solutions, the leader in population health enablement technology and solutions, ranks on the 2024 Inc. 5000, its annual list of the fastest-growing private companies in America. The prestigious ranking provides a data-driven look at the most successful companies within the economy’s most dynamic segment—its independent, entrepreneurial businesses. Microsoft, Meta, Chobani, Under Armour, Timberland, Oracle, Patagonia, and many other household-name brands gained their first national exposure as honorees on the Inc. 5000.

“Being recognized on the Inc. 5000 for the 6th time is a tremendous honor and a testament to the unwavering commitment of the entire Lightbeam team,” says Pat Cline, Chief Executive Officer of Lightbeam Health Solutions. “This achievement highlights our relentless pursuit of excellence and innovation as we continue to expand our capabilities and deliver transformative solutions in value-based care. We are incredibly proud of the progress we’ve made and deeply grateful for the support of our clients and partners. This recognition fuels our drive to achieve even greater success in the future.”

The Inc. 5000 class of 2024 represents companies that have driven rapid revenue growth while navigating inflationary pressure, the rising costs of capital, and seemingly intractable hiring challenges. Among this year’s top 500 companies, the average median three-year revenue growth rate is 1,637 percent. In all, this year’s Inc. 5000 companies have added 874,458 jobs to the economy over the past three years.

For complete results of the Inc. 5000, including company profiles and an interactive database that can be sorted by industry, location, and other criteria, go to http://www.inc.com/inc5000. Companies on the 2024 Inc. 5000 are ranked according to percentage revenue growth from 2020 to 2023. To qualify, companies must have been founded and generating revenue by March 31, 2020. They must be U.S.-based, privately held, for-profit, and independent—not subsidiaries or divisions of other companies—as of December 31, 2023.

“One of the greatest joys of my job is going through the Inc. 5000 list,” says Mike Hofman, who recently joined Inc. as editor-in-chief. “To see all the intrigue and surprising ways that companies are transforming sectors, from health care and AI to apparel and pet food, is fascinating for me as a journalist and storyteller. Congratulations to this year’s honorees, as well, for growing their businesses fast despite the economic disruption we all faced over the past three years, from supply chain woes to inflation to changes in the workforce.”

Lightbeam was recently recognized as 2024 Best in KLAS® for its Deviceless Remote Patient Monitoring® solution. The Lightbeam platform incorporates advanced capabilities like prescriptive AI to accelerate value-based care performance. By enabling payers and providers to align clinical and financial outcomes, Lightbeam eliminates administrative burdens and lowers total cost of care while improving health equity. Additionally, Lightbeam was further acknowledged as a 2024 Finalist for Microsoft’s Healthcare and Life Sciences Partner of the Year. To explore how Lightbeam’s prescriptive AI reduces cost like avoidable readmissions, download the case study here.

“Being recognized on the Inc. 5000 for the 6th time is a tremendous honor and a testament to the unwavering commitment of the entire Lightbeam team,” says Pat Cline, Chief Executive Officer of Lightbeam Health Solutions. “This achievement highlights our relentless pursuit of excellence and innovation as we continue to expand our capabilities and deliver transformative solutions in value-based care. We are incredibly proud of the progress we’ve made and deeply grateful for the support of our clients and partners. This recognition fuels our drive to achieve even greater success in the future.”

The Inc. 5000 class of 2024 represents companies that have driven rapid revenue growth while navigating inflationary pressure, the rising costs of capital, and seemingly intractable hiring challenges. Among this year’s top 500 companies, the average median three-year revenue growth rate is 1,637 percent. In all, this year’s Inc. 5000 companies have added 874,458 jobs to the economy over the past three years.

For complete results of the Inc. 5000, including company profiles and an interactive database that can be sorted by industry, location, and other criteria, go to http://www.inc.com/inc5000. Companies on the 2024 Inc. 5000 are ranked according to percentage revenue growth from 2020 to 2023. To qualify, companies must have been founded and generating revenue by March 31, 2020. They must be U.S.-based, privately held, for-profit, and independent—not subsidiaries or divisions of other companies—as of December 31, 2023.

“One of the greatest joys of my job is going through the Inc. 5000 list,” says Mike Hofman, who recently joined Inc. as editor-in-chief. “To see all the intrigue and surprising ways that companies are transforming sectors, from health care and AI to apparel and pet food, is fascinating for me as a journalist and storyteller. Congratulations to this year’s honorees, as well, for growing their businesses fast despite the economic disruption we all faced over the past three years, from supply chain woes to inflation to changes in the workforce.”

Lightbeam was recently recognized as 2024 Best in KLAS® for its Deviceless Remote Patient Monitoring® solution. The Lightbeam platform incorporates advanced capabilities like prescriptive AI to accelerate value-based care performance. By enabling payers and providers to align clinical and financial outcomes, Lightbeam eliminates administrative burdens and lowers total cost of care while improving health equity. Additionally, Lightbeam was further acknowledged as a 2024 Finalist for Microsoft’s Healthcare and Life Sciences Partner of the Year. To explore how Lightbeam’s prescriptive AI reduces cost like avoidable readmissions, download the case study here.

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Through the offering, an organization can gain access to a range of core language services, including video remote interpreting, over-the-phone interpreting, in-person interpreting, and translation. In addition, SPS will offer wraparound services and solutions tailored to the specific needs of each organization, determined through a thorough analysis and evaluation of their language access program.

“Operating a language service department has traditionally been seen as a cost associated with doing business. With SPS, we are changing this narrative and redefining language services as a strategic part of patient care that instead has the ability to reduce cost by addressing common issues like longer lengths of stay, missed appointments and higher readmissions driven by a lack of language service resources,” said Jacobia Solomon, President, AMN Language Services. “The launch of SPS represents a significant milestone for the healthcare industry, and we are proud to be at the forefront of this innovative approach to language access in healthcare.”

SPS addresses common challenges faced by healthcare organizations, including limited resources, high staff turnover, compliance issues, and difficulty in serving limited English proficient populations. By leveraging AMN Healthcare’s industry and operational expertise, SPS aims to enhance the reliability, efficiency, and cost-effectiveness of language access programs while improving patient outcomes. Leaders at Yuma Regional Medical Center, an SPS pilot site, have begun experiencing the solution’s effects.

“Our staff have been very impressed with the speed at which our patients are getting connected with an interpreter and with the quality of the interpretation that is occurring,” said Tina Rube, Director of Patient Experience & Care Advocacy for Yuma Regional Medical Center. “We finally have the resources to fully provide for our many non-English speaking patients.”

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Rhapsody, a global leader in digital health enablement and interoperability, today announced the results of a 2024 Forrester Consulting Total Economic Impact (TEI) study. The study reveals a significant 193% return on investment (ROI) over three years for interviewed health technology teams using Rhapsody integration solutions, offering an efficient and compliant approach to healthcare data integration.

The TEI study displays how the healthcare specialized solutions from Rhapsody meet the complex needs of healthcare technology organizations, including managing intricate data standards like FHIR, HL7, and DICOM, while ensuring compliance with global data privacy regulations. Unlike broad cross-industry platforms, the Rhapsody healthcare-specific approach enables faster, more scalable growth with fewer resources.

Key findings from the study are conveyed through the lens of a composite healthcare technology organization with $25M in annual recurring revenue, representative of interviewed Rhapsody customers. In addition to a 193% ROI, the study found a net present value of $1.59 million over three years, with a payback period of less than six months, plus:

• $1M in avoided costs (per $25M ARR) over three years due to streamlined staffing and reduced need for new hires.
  
• 30 days faster time to market per customer onboarded, leading to quicker revenue realization.
  
• Threefold increase in throughput and a significant reduction in time to production from weeks to days, enhancing operational efficiency.

The study demonstrates how Rhapsody integration solutions drive significant value by improving engineer and analyst efficiency, accelerating development lifecycles, and reducing time to market. Chief Technology and Product Officers at health technology companies of all sizes can use the study’s findings to build a business case for the potential cost savings and revenue generation for their own organizations.

The Chief Information Officer of a health technology company specializing in AI surgical platforms told Forrester, “By leveraging Rhapsody, we save valuable resources and focus on our core competency. Trusting the experts in software integration allows us to optimize our investments and achieve unparalleled efficiency. Let us leave the data intake and acquisition to those who know it best, so we excel in what truly matters to us.”

Sagnik Bhattacharya, CEO of Rhapsody, stated, “Rhapsody’s value lies in our deep specialization in healthcare data integration. The customers interviewed by Forrester clearly articulate how Rhapsody technology enabled their success and drove measurable ROI. Rhapsody is the most comprehensive and tech forward data integration platform; and we expect that this independent study will give our customer champions a clear framework to quantify monetary value to their organization.”

To discover how to build a business case for how Rhapsody could deliver benefits and ROI to your own organization, based on the study’s results, download the full Forrester Total Economic Impact study. Contact Rhapsody for a personalized consultation.

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Creating a Patient-Centered Healthcare Network Spanning Multiple Cities

From its inception, Kaiyi Healthcare has carved a unique path in healthcare. Originated as a joint venture between Columbia Pacific Management (CPM) in the US and Sheares Healthcare in Singapore, Columbia China gained further momentum in April 2020 when Swire collaborated with CPM to co-invest in the JV. To address the specific needs of the Chinese healthcare market, Kaiyi Healthcare has spun off from Columbia China to grow independently.

Based in Shanghai, Kaiyi Healthcare has expanded its reach to establish and manage several medical institutions in cities such as Wuxi and Jiaxing. The company provides high-quality medical services that meet the health needs of the general public, alongside personalized and customized medical services for affluent individuals. Currently, Kaiyi Healthcare manages the specialized hospital Shanghai Kaiyuan Orthopaedics Hospital, and two robust general hospitals: Wuxi Kaiyi Hospital and Jiaxing Kaiyi Hospital.

Throughout its development, Kaiyi Healthcare has remained committed to a patient-centered mission to provide patients and their families with better medical care. By establishing a comprehensive healthcare network and introducing cutting-edge medical technologies, Kaiyi Healthcare aims to deliver professional, personalized, and high-quality medical services, fulfilling its vision to become the preferred healthcare provider for Chinese consumers.

Building Core Competitiveness with a Multifaceted Approach to Innovation

“2024 marks a significant year for Kaiyi Healthcare as it ushers in a new stage of development and leapfrog growth for the three hospitals under our umbrella,” said the Kaiyi Healthcare CEO, Mr. Peter Wang.

Developing Disciplinary Competence through Localization

In terms of building disciplinary competency, Kaiyi Healthcare emphasizes local adaptation, gaining deep insights into the geographical characteristics of the Yangtze River Delta region and the needs of the local population. By aligning market demand with the medical expertise of its hospitals, the company adopts an approach that emphasizes core areas of medical practice alongside unique specialized services to address the diverse needs of patients in the region.

Shanghai Kaiyuan Orthopaedics Hospital, for instance, has deployed an innovative integrated diagnosis and treatment system for orthopaedic surgery and rehabilitation. The system specializes in spine, joint, and sports medicine, while also pioneering distinctive disciplines in hip preservation and minimally invasive orthopaedics. Kaiyuan continues to break new ground in medical technology, successfully implementing robot-assisted surgeries and 3D digital printing technology. In doing so, the hospital strives to provide patients with an exceptional healthcare experience through professional technologies and comprehensive services.  

Wuxi Kaiyi Hospital has further expanded its influence in the cardiovascular field by attracting top-tier talent and leveraging its advanced imported medical equipment and cath lab. The hospital is actively developing new, cutting-edge approaches to cardiac interventions and intravascular ultrasound (IVUS), with the goal of establishing its cardiology department as a leading municipal specialty in Wuxi City.

Jiaxing Kaiyi Hospital continues to enhance its pediatric specialties, focusing on sub-specialties within pediatric internal medicine. The hospital plans to launch pediatric night outpatient clinics and pediatric ward services in the fourth quarter of 2024 to better meet clinical needs.

Enhancing Service Efficiency with Operational Excellence

Mr. Peter Wang indicated, “In the healthcare industry, time is equivalent to a race against life, and every moment is critical. As a result, efficient operation is key to improving the quality of healthcare services and is the cornerstone of achieving sustainable development.”

Kaiyi Healthcare has fully integrated the modern lean management philosophy into all aspects of hospital operations and management. By reshaping business processes, optimizing resource allocation, and strengthening value chain management, the company has enhanced the quality of healthcare services while reducing patient wait time and healthcare costs. In 2024, Kaiyi Healthcare has made significant progress in diversifying patient sources and business areas while effectively controlling operational costs and optimizing resource efficiency. Notable initiatives include the online patient operations at Shanghai Kaiyuan Orthopaedics Hospital, the 120 EMS at Wuxi Kaiyi Hospital, and the expansion of VIP expatriate clients at Jiaxing Kaiyi Hospital. These efforts have opened up new possibilities for Kaiyi’s business model.

Optimizing Healthcare Experience through Innovation

Kaiyi Healthcare is currently at a critical stage of digital transformation. Notably, Jiaxing Kaiyi Hospital has obtained an Internet hospital license, marking a significant milestone in the implementation of Kaiyi Healthcare’s initiative for online medical services.

Kaiyi Healthcare plans to build a unified digital management system for planning, implementation, and management through the integration of digital technologies. This system will merge online and offline medical resources, break down barriers between disciplines and medical insurance services, and capture comprehensive healthcare data. By leveraging medical large language models, AI, and other advanced technologies, Kaiyi seeks to further enhance the online medical services. “Moving forward, Kaiyi Healthcare will continue to drive technological innovation in areas such as AI-assisted diagnosis, ChatAI-enabled intelligent digital analysis, and digital patient support services, allowing patients to experience the benefits of technology in healthcare,” stated Mr. Peter Wang.

Creating a Corporate Culture That Prioritizes Patient Care

An excellent corporate culture is indispensable for the growth of the company. “Kaiyi Healthcare has built a unique culture centered on Professionalism, Passion, and Target-orientation (PPT),” explained Mr. Peter Wang. Kaiyi Healthcare instills in its healthcare professionals a profound sense of mission—to uphold passion and composure while addressing patient challenges, enhancing medical care for patients and their families, and ultimately delivering a more compassionate medical service experience. This mission has earned Kaiyi Healthcare continuous recognition and gratitude from government entities, as well as patients and their families.

Driven by this mission, more medical specialists and industry leaders have joined Kaiyi Healthcare to help advance its technology and disciplines. In 2023, the company’s hospitals brought in 13 seasoned clinicians above the associate professor level, and more than 10 additional specialists are anticipated to join in 2024.

Committed to a Long-Term Vision in a Growing Healthcare Sector

The private healthcare market in the country is poised for substantial growth, presenting a significant opportunity that has bolstered confidence in Kaiyi Healthcare’s future development. Recognizing the potential, Kaiyi Healthcare is committed not only to expanding its reach but also to elevating the standards of medical care and service quality. This balanced approach aims to solidify its position in a competitive industry while ensuring sustainable progress.

Mr. Peter Wang added, “The future of the medical industry lies in innovation and service. Only through continuous innovation can we meet the growing health needs of patients; only by providing high-quality services can we win their trust and confidence. Looking ahead, Kaiyi Healthcare will continue to uphold a patient-centered service approach, deepen its brand essence, and expand its reach. By continuously optimizing the medical service model and incorporating advanced medical technologies and management concepts, Kaiyi Healthcare is committed to delivering premium, professional medical services to domestic patients and contributing to the realization of a healthy China.”

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Infor, the industry cloud company, today announced that Sanford Health, the largest rural health care system in the United States serving more than 1.4 million patients, will implement a suite of Infor cloud-based applications designed for healthcare to streamline and modernize functions across its network. The integrated health system has 48 medical centers, 211 clinic locations, more than 160 Good Samaritan Society senior living centers, 2,900 Sanford physicians and advanced practice providers, 540 active clinical trials and nine world clinic locations around the globe. With Infor, Sanford Health will be able to better leverage data to break down silos across departments, streamline workflows, and gain real-time insights, freeing up caregivers to prioritize care.

Sanford Health decided to partner with Infor because of its modern, cloud-based architecture, and ability to offer health care-specific finance and supply chain solutions that meet the organization’s requirements without extensive manual customization. In addition, Infor’s solutions integrate seamlessly into Sanford’s current business needs and processes, providing leadership with real-time data. Lastly, Infor was able to clearly demonstrate its commitment to health care, extensive product roadmap, and forward-thinking approach.

Infor Healthcare offers industry specialized applications that provide one source of truth, with cloud flexibility, anytime, anywhere access, a beautiful user interface and healthcare-specific analytics. Its innovative system has the capabilities to unify processes across the employee lifecycle while seamlessly integrating with the core enterprise financial management and payroll solutions.

“We look forward to supporting Sanford Health in achieving greater operational efficiency and delivering exceptional health care services to the communities they serve,” said Steve Fanning, senior vice president, Infor.

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Funding will support expanded commercialization efforts for PreciseBreast risk assessment

PreciseDx®, a leading innovator in oncology diagnostics leveraging Artificial Intelligence (AI) for new, morphology-driven disease analysis, today announced that it has raised $20.7 million in Series B funding, bringing its total funding to date to $31.5 million. The round was led by Eventide Asset Management (“Eventide”), which invests in biotech and life science healthcare companies seeking solutions for unmet clinical needs.

Additional participants in the round include Labcorp, Quest Diagnostics, and GenHenn Capital Venture, along with existing investors.

“Our team continues to advance breast cancer diagnostics by delivering faster, more accurate data, in a cost-efficient method. This allows clinical care teams to make better informed clinical decisions resulting in improved patient outcomes,” said Eric Converse, Founding Board Member of PreciseDx. “This capital infusion sets the stage for our next phase of continued in-depth clinical trials to validate PreciseBreast in a specific clinical setting and market entry point.”

“We’re excited about PreciseDx, the milestones accomplished to date, and the potential for improving patient care in the near future,” said Westley Dupray, CFA, Research Analyst, Principal at Eventide. “We expect this financing will help accelerate the validation process for PreciseBreast and its potential to improve patient risk assessments, clinical outcomes, and healthcare efficiency.”

The funding comes on the heels of a number of key achievements by PreciseDx, including completion of two successful validation studies (analytical and clinical); receipt of CLIA Standard approval and CLEP NYSDOH review on the PreciseBreast assessment; a Cost Impact Study published by the Journal of Medical Economics; and the addition of new key collaborations, such as UCLA, COTA and Baptist Health South Florida, and Baylor Scott & White Health.

“Securing Series B funding not only signals PreciseDx’s continued achievements, but also underscores the trust and confidence in the Company’s trajectory,” added Converse.

Aquilo Partners, L.P. acted as financial advisor and McDermott Will & Emery as legal advisor to PreciseDx.

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ADVI Health is pleased to announce the acquisition of Partnership for Health Analytic Research (PHAR), a global health technology assessment (HTA) and health economics and outcomes research (HEOR) consultancy, known for providing high-impact, data-driven insights to some of the largest biopharmaceutical sponsors and clients. This addition to ADVI’s Strategic Analytics, Value and Economics (SAVEs) team bolsters ADVI’s data analysis and value strategy capabilities with significant HTA/HEOR, primary research, literature review, patient registry expertise, and capabilities.

“As the healthcare landscape continues to evolve, so do our clients’ needs. With decades of experience and deep-bench knowledge, PHAR brings a depth of expertise that complements our SAVEs and Market Access teams. I am excited to improve and expand our service offerings for our clients moving forward,” said Marc Samuels, CEO of ADVI.

The acquisition underscores ADVI’s mission and vision to be the go-to-market partner for life sciences innovators worldwide by helping our clients advance patient access, accelerate time to reimbursement, and achieve optimal business results by providing data-informed strategy and access solutions that create opportunity, generate evidence, optimize strategy, and fund growth. By integrating PHAR’s data analytics experts, most known for their implementation science, ADVI expands its work with the evidence behind clinical and retrospective value assessments.

Marc and Caitlin Sheetz, Head of SAVEs, welcome Dr. Michael Broder, founder of PHAR, Eunice Chang PhD, and the rest of the PHAR team. “Joining ADVI is an exciting opportunity for our team. We are looking forward to working across solution areas and learning new ways to use our data to create more impactful results for the clients we have had for so many years and the new ones we will meet through our partnership with ADVI,” said Dr. Broder, PHAR CEO and Founder. “With the growing number of novel therapeutics coming to market, it is more important than ever that we can use the data available to show the true value of these products, especially when it comes to brand launch, enabling access to on-market products, and bolstering life cycle performance.”

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NRC Health, a recognized leader in delivering innovative solutions and data-driven insights to improve healthcare experiences, announced a new suite of next-gen AI-enabled products, along with an acquisition and new partnership, today at HUB24.

“Healthcare experiences are human experiences, and the use of technology has often come at the expense of human connections—until now,” said Christophe Louvion, Chief Product and Technology Officer at NRC Health. “All of our next-generation products are powered by NRC Health’s secure, private AI engine Huey, healthcare’s first AI engine and large language model (LLM) trained exclusively on the personalized data that matters most to clinical teams and patients.”

Huey is built with a moral framework that ensures that the technology closely aligns with human-centric, societal values to deliver compassionate feedback, relevant coaching, and the next best actions to frontline teams, leaders, and clinicians.

NRC Health’s holistic healthcare experience management framework breaks down the barriers often created by traditional technology and restores Human Understanding® across the healthcare experience. New AI-powered products include:

• nGage: AI-powered listening that captures unstructured feedback via video, image, and free text, in the natural voice and language of patients, employees, and community members along their journey.
• nQuire: Smart feedback summaries to make meaning out of mountains of data, delivering aggregated feedback in seconds based on actual comments from a customer database.
• nVolve: Intelligent, predictive conversation enablement for patient experience (PX) and employee experience (EX) use cases, built with the best of Nobl (acquired by NRC Health).
• nLighten: Personalized narrative and competency summaries, gamified with actionable coaching for clinical teams on the frontline.
• nAct:Smart service recovery that instantly drafts recommended responses to empower teams to resolve alerts better and faster without adding to their workload.

At HUB24, NRC Health also announced their acquisition of Nobl—the leader in advanced rounding solutions for healthcare organizations—and a partnership with Medallia to solve issues that directly impact human healthcare experiences for consumers and employees.

“With the complexity and demands associated with healthcare delivery today, it’s critical to take a human-centered approach—and Nobl can help us do just that,” said Jennifer Baron, Chief Experience Officer at NRC Health. “Nobl’s rounding solutions provide patient and employee feedback for leaders to directly act on key issues and improve healthcare experiences in real time.”

NRC Health’s partnership with Medallia strengthens the organization’s capabilities in consumer experience (CX) and employee experience (EX). Medallia’s globally tested technology equips NRC Health with scalable tools that support end-to-end journey listening—illuminating CX blind spots and broad multi-industry EX benchmarks—as well as advanced reporting, embedded action workflows, and sophisticated contact-center offerings.

“We are thrilled to add the advanced technology solutions from Nobl and Medallia to our comprehensive suite of AI-enabled products—all built on Human Understanding,” said Vinitha Ramnathan, Chief Product Officer at NRC Health. “The use of this technology offers insights that allow health systems to illuminate and improve what matters most to patients, employees, and the communities they serve, while delivering unparalleled value to our customers.”

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Accelerating clinical trial development and discovering potential novel treatments for neurological, psychiatric and infectious diseases

DiagnaMed Holdings Corp. (“DiagnaMed” or the “Company”) (CSE: DMED) (OTCQB: DGNMF), a healthcare technology company focused on brain health using AI, announces it is expanding the use of its novel BRAIN AGE® Brain Health AI Platform (“BRAIN AGE®”) through leveraging its electroencephalograph (“EEG”) data from research studies and future data collection, and applying it to build a potential drug discovery and clinical research AI platform. EEG provides a real-time readout of brain-wave activity in different brain regions and can measure a drug effect on the brain. BRAIN AGE® has the potential to accelerate patient recruitment for clinical trials, data analysis, drug development go/no-go decisions and new treatment options for neurological, psychiatric and infectious diseases.

BRAIN AGE® Brain Health AI estimates brain age by recording brain-wave activity from multiple brain regions and calculating the data with a proprietary machine-learning model. Certain drugs acting on the brain can generate a consistent EEG effect and produce models useful for developing novel drug analogs¹ and potential drug repurposing ideas. In studying the effects of drugs on the brain via EEG, researchers can classify and identify drugs according to their mechanism of action on brain activity.²

Clinical Validation of BRAIN AGE® Brain Health AI Platform

BRAIN AGE® Brain Health AI can assess if a brain is aging more quickly or more slowly than is typical for healthy individuals. Brain age is estimated by collecting neural activity data of the brain with a low-cost and easy-to-use electroencephalogram headset and calculating the data with a proprietary machine-learning model. In addition, BRAIN AGE® Brain Health AI can assess if a person has a healthy brain or is in the early stage of cognitive decline. Brain health is scored by taking a clinically validated assessment for brain resilience, vulnerability and performance functions. Individuals can seek out personalized diagnostics and interventions, such as medication or lifestyle changes, that may help decrease cognitive decline development or progression.

In a first-of-a-kind peer-reviewed paper in Frontiers in Neuroergonomics, titled “Brain-age estimation with a low-cost EEG-headset: effectiveness and implications for large-scale screening and brain optimization”³, BRAIN AGE®, as announced in a press release by Drexel University, Prof. Kounios was quoted regarding the clinical potential of BRAIN AGE®: “It can be used as a relatively inexpensive way to screen large numbers of people for vulnerability to age-related. And because of its low cost, a person can be screened at regular intervals to check for changes over time,” Kounios said. “This can help to test the effectiveness of medications and other interventions. And healthy people could use this technique to test the effects of lifestyle changes as part of an overall strategy for optimizing brain performance.”⁴

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Clarium, Inc. the healthcare technology company revolutionizing hospital supply chain operations, today announced a $10.5M strategic financing round. The investment was led by General Catalyst, with backing from Kaiser Permanente Ventures, Texas Medical Center Venture Fund, Yale New Haven Health, as well as existing investors AlleyCorp, 1984 Ventures, Alumni Ventures, and others. The funding takes Clarium’s total capital raised to date to $16M.

Alongside the strategic financing, Clarium introduced Astra OS, its proprietary AI-powered workflow platform and data ecosystem. Astra OS, which was designed and built in collaboration with several leading health systems, empowers providers to optimize and automate their supply chain operations with insights to achieve millions of dollars in cost savings and productivity improvements annually.

“Health systems have a transformational opportunity to reimagine their supply chains by partnering with Clarium,” said Steve Liou, Founder and CEO of Clarium. “Our AI-powered platform and data ecosystem, Astra OS, brings hospitals and providers to the cutting edge of technology and helps to dramatically optimize spend, enhance workforce productivity, and ultimately improve patient outcomes.”

With this financing, Clarium plans to continue recruiting exceptional talent across data science, engineering, sales, product, and customer success to meet the needs of its growing customer base. The Company will use the investment to integrate further with existing partners (CommonSpirit, Yale New Haven Health, Geisinger, Ochsner Health, Boston Children’s Hospital) and build programs with additional health systems. The Company will also build on and refine its platform’s product offerings and continue to invest in generative AI and large language model technologies to augment Clarium’s software platform and applications.

“We’ve seen firsthand the need for tools to help healthcare executives create resilient supply chains. Clarium’s Astra OS is aiming to fill a market gap with its end-to-end enterprise platform for supply chain operations. Through deep integrations and the application of generative AI, we believe Clarium will drive a paradigm shift in supply chain efficiency. We’re excited to partner with Steve and the rest of the Clarium team on this next phase of growth as they scale across the country,” said Reva Nohria, partner at General Catalyst.

Clarium is solving a critical problem in the healthcare industry

Historically, healthcare data has been fragmented across multiple systems for hospitals and suppliers. This has led to significant challenges in inventory management, demand planning, data accuracy, and workforce efficiency, which has contributed to the industry overspending on supply chain products and related operations by over $25B each year. The COVID-19 pandemic exacerbated these gaps and inefficiencies dramatically – against this backdrop, Clarium was founded in early 2020 with the fundamental mission of helping hospitals improve their supply chain operations and be fully prepared to combat the next major pandemic or shortage with game-changing technology.

Astra OS is Clarium’s AI-powered workflow platform that brings together real-time data to improve visibility, collaboration, and resiliency across all departments and teams. On top of Astra OS is Clarium’s suite of workflow applications that deploy intelligent automation to hospitals, enhancing their productivity by proactively managing inventory and resolving supply disruptions (Disruption Monitor), automating substitute approvals (Substitute Manager), streamlining procedure card management (Card Optimizer), and more, with other applications in development.

Since integrating Astra OS, Clarium’s health system partners have identified an average of $10M+ in cost savings and productivity gains in their supply chain operations, including the following:

• 50% decrease in average disruption resolution time
• 63% decrease in average substitute approval time
• 3.7x growth in clinically validated substitutes approved

“Clarium’s ability to leverage artificial intelligence for data unification and predictive insights has proven to be invaluable to our organization,” said Jacqueline Epright, Vice President of Supply Chain at Yale New Haven Health. “We now have over 300 users across seven departments actively engaged in Clarium’s platform, and we’re excited to continue expanding our partnership further.”

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